RESEARCH GRANTS
From September 2017-December 2020, Anthony’s Avengers DIPG Foundation operated under Michael Mosier Defeat DIPG® Foundation as, Anthony’s Avengers Defeat DIPG® Foundation. Over three years, with the combined efforts of Defeat DIPG® Network Foundations and ChadTough Foundation, more than $6.1 million was awarded to fund DIPG-specific research projects. These grants are specific to DIPG research and include Research Grants, New Investigator Grants and Fellowship Grants.
RESEARCH GRANTS
David Ashley, Duke University “Recombinant Attenuated Poliovirus Immunization Vectors Targeting H#.(K27M) in DIPG”
Catherine Flores, University of Florida “Enhancing efficacy of adoptive immunotherapy against DIPG using hematopoietic cells.”
Stephanie Galban, University of Michigan “Targeting Cancer Stem Cells in DIPG.”
Nalin Gupta and Daniel Lim, University of California San Francisco “Use of a Long Non-coding RNA (IncRNA) as a Therapeutic Target in DIPG.”
Daphne Haa-Kogan and Brendan Price, Dan Farber Cancer Insitute “Dependence of DIPGs on DNA polymerase θ for DNA repair defines a new therapeutic target.”
Michelle Moje, Stanford University “The Tumor Microtube Network in DIPG: Targeting a Possible ‘Achilles Heel’ Required to Defeat DIPG.”
Hideho Okada, University of California San Francisco “Next-generation CAR T cell therapies for treatment of DIPG, utilizing sequential ‘prime-and-kill’ circuits to achieve safe and effective tumor targeting”
NEW INVESTIGATOR GRANTS
SAMEER AGNIHOTRI, UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE “Therapeutic Targeting of Metabolic Vulnerabilities in DIPG”
Pratiti Bandopadhayay, Dana-Farber Cancer Institute “Characetorizing long non-coding RNAs as therapeutic targets in Diffuse Intrinsic Pontine Glioma”
Matthew Dun, Hunter Medical Research Institute at the University of Newcastle “Unlocking oncogene addition to identify synergistic treatment targets for the treatment of DIPG”
Stephen Mack, Baylor College “Interrogating the role of POU Transcription Factor Driven ERV Activation in H3K27M Diffuse Midline Glioma”
Zach Reitman, Duke University “Enhancing the efficacy of radiation therapy for DIPG”
James Stafford, University of Vermont “ONC201 in DIPG; establishing mechanism, enhancing efficacy and determining long-term phenotypic consequences”
Sujatha Venkatataman, University of Colorado Denver “MIC2 inhibition mediated apoptosis in DIPG”
Nicholas Vitanza, Fred Hutchinson Cancer Research Center “Optimal combinatorial targeting of HDAC inhibition and radiation in DIPG”
Fellowship Grants
Jamie Anastas, Harvard University/Boston Children’s Hospital "Targeting chromatin regulation to treat DIPG”
Chan Chung, University of Michigan “Targeting DIPGs by interrupting metabolic pathways”
Alan Jiao, Boston Children’s Hospital “Dissecting mechanisms of H3K27M oncohistone function in DIPG”
Nneka Mbah, University of Michigan “Therapeutic Targeting of the Disrupted Metabolic State in DIPG to Induce Ferroptotic Cell Death”
Eshini Pandithatatna, Dana-Farber Cancer Institute “Targeting epigenetically induced vulnerabilities in DIPG”
Chen Shen, Northwestern University “Dissection of ATRX in Duffuse Intrinsic Pontine Glioma”
Xu Zhang, Columbia University “Mechanistic studies on the WNT5A signal pathway in DIPG tumor”